Media Highlights
Wellington Lab hosts first-ever open house
Djavad Mowafaghian Centre For Brain Health
September 16, 2025
This graduate student-led initiative was focused on providing trainees with an opportunity to practice their knowledge dissemination skills to a general audience in a relaxed and low-stress environment. Read article ›
B.C. doctors studying brain injuries in survivors of intimate partner violence
CBC News
July 22, 2025
Multiple recent cases of fatal intimate partner violence in B.C. have advocates like Dr. Cheryl Wellington calling on the province to declare the violence a public health crisis. Watch segment ›
A Hidden Path to Alzheimer’s Disease for Women
BrightFocus Foundation
July 2, 2025
Women who survive intimate partner violence may face long-term brain health risks. This feature includes work by CFNBI Academic Lead Dr. Cheryl Wellington on IPV-related brain injury and dementia risk. Read article ›
Wellington lab acquires Canada’s first ARGO HT System for advanced biomarker detection
Djavad Mowafaghian Centre For Brain Health
October 28, 2024
Dr. Cheryl Wellington’s lab recently acquired Canada’s first Alamar ARGO HT System, an advanced, fully automated analyzer designed to detect and quantify biomarkers in biological samples with ultra-high sensitivity. Read article ›
UBC researchers receive $3.4M to address brain injuries in survivors of intimate partner violence
University of British Columbia
June 11, 2024
Researchers from the University of British Columbia (UBC) to lead a community-based project aimed at improving the diagnosis of brain injury in survivors of intimate partner violence and exploring possible connections to Alzheimer’s disease and related dementias. Read article ›
COVID-19 Collaboration Saves Lives of ICU Patients
Djavad Mowafaghian Centre For Brain Health
October 26, 2020
As a major collaborative effort between frontline healthcare and academia, a province-wide biobank would bring together the individual efforts of teams like Dr. Sekhon’s and Dr. Wellington’s who are racing to understand the effects of SARS-CoV-2 on the body to discover new treatments. Read article ›
Publications
2026
Go, KD, Hutchison, J, Wang, K, Karikari, TK, Mondello, S, Diaz-Arrastia, R, Puccio, A, Stukas, S, Cooper, JG, Wellington, CL. Biases and consistency of different assay methods for neurological biomarkers using Quanterix single-molecule-array technology: A comparative study of the secondary analysis method. 2026 March, 31: 100147. doi.org/10.1016/j.neumar.2025.100147
2025
Bird, JD; Hornby, L; Hirsch-Reinshagen, V; Allen, CP; Isac, G; Gooderham, PA; Shemie, SD; Dhanani, S; Thiara, S; Stukas, S; Grey, R; Foster, DA; Maier, LE; LeBlanc, A; Kanji, HD; Morelli, TF; Agbay, AM; Wellington, CL; Chahal, D; Belanger, EC; Ren, H; Mattu, PS; Su, S; Hrazdil, CT; Percy, J; Sangha, P; Plewes, LV; Sweet, DD; Romano, KR; Vu, EN; Chittock, DR; Dhingra, VK; Henderson, WR; Garraway, N; Hameed, SM; Finlayson, GN; MacLeod, DB; Gibbons, TD; Ainslie, PN; Hoiland, RL; Griesdale, DE; Ronco, JJ; Sekhon, MS. Characterizing the Physiology of Circulatory Arrest in Humans. 2025 October 16, 31: 3542–3552. doi.org/10.1038/s41591-025-03889-z
Harper, M.I.; McKinney, K.; McLennan, C.; Adhikari, S.P.; Ghodsi, M.; Cooper, J.G.; Stukas, S.; Maldonado-Rodroguez, N.; Agbay, A.; Morelli, T.; Nouri Zadeh-Tehrani, S.; Lorenz, B.R.; Rothlander, K.; Smirl, J.D.; Wallace, C.; Symons, G.F.; Brand, J.; Christie, B.R.; Gawryluk, J.; Falkenberg, A.; Varto, H.; Mason, K.; Shultz, S.R.; van Donkelaar, P.; Wellington, C.L. Advocates, Academics, Survivors and Clinicians to END Intimate Partner Violence (ASCEND-IPV) initiative: a prospective observational case-control study protocol to identify plasma biomarkers of intimate partner violence (IPV)-caused brain injury (BI). 2025 Sept 16; 15 (9): :e098025. doi: 10.1136/bmjopen-2024-098025
Caron, NS.; Fan, J.; Ma, D.; Yung, A.; Ko, S.; Bale, K.; Anderson, C.; Kozlowski, P.’ Pouladi, M.; Wellington, C.; Hayden, M. Molecular and imaging biomarker responses to brain mutant HTT lowering in a mouse model of Huntington disease. 2025 Dec 9; 36 (4): 102710. doi: doi.org/10.1016/j.omtn.2025.102710
Stukas, S.; Goshua, G.; Conway, E.M.; Lee, A.Y.Y.; Hoiland, R.L.; Sekhon, M.S.; Chen, L.Y.C. ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients. 2025 Apr 2; 20(4):e0320251. doi: 10.1371/journal.pone.0320251. PMID: 40173171
Qiu, Y.; Jacobs, D.M.; Messer, K.; Salmon, D.P.; Wellington, C.L.; Stukas, S.; Revta, C.; Brewer, J.B.; Léger, G.C.; Askew, B.; Donahue, L.; Kaplita, S.; Coric, V.; Qureshi, I.A.; Feldman, H.H.; Alzheimer’s Disease Cooperative Study T2 Protect AD Study Group. Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease. 2025 May 02; 17 (1). doi: doi: 10.1186/s13195-025-01745-3. PMID: 40317057 .
Silveira C.R.A.; Coleman K.; Borron, K.; Tirona, R.G.; Rupar, C.A.; Zou, G.; Hegele, R.A.; Wellington, C.; Stukas, S.; Finger, E.C.; Bartha, R.; Morrow, S.A.; Wells, J.; Borrie, M.; Mahuran, D.; MacDonald, P.A.; Jenkins, M.E.; Jog, M.S.; Dresser, G.; Speechley, M.; Fox, S.; Feagan, B.; Mendonca, D.A.; Mayich, M.; Sharma, M.D.; Pandey, S.K.; Pasternak, S.H. Ambroxol as a Treatment for Parkinson Disease Dementia. 2025 June 30; e251687. doi: doi: 10.1001/jamaneurol.2025. PMID: 40587145
Muir RT, Stukas S, Cooper JG, Beaudin AE, McCreary CR, Gee M, Nelles K, Nukala N, Valencia J, Kirmess KM, Black SE, Hill MD, Camicioli R, Wellington CL, Smith EE. Plasma biomarkers distinguish Boston Criteria 2.0 cerebral amyloid angiopathy from healthy controls. Alzheimers Dement. 2025 Mar;21(3):e70010. doi: 10.1002/alz.70010. PMID: 40156276; PMCID: PMC11953569.
Sun M, Symons GF, Spitz G, O’Brien WT, Baker TL, Fan J, Martins BD, Allen J, Giesler LP, Mychasiuk R, van Donkelaar P, Brand J, Christie B, O’Brien TJ, O’Sullivan MJ, Mitra B, Wellington C, McDonald SJ, Shultz SR. Pathophysiology, blood biomarkers, and functional deficits after intimate partner violence-related brain injury: Insights from emergency department patients and a new rat model. Brain, Behavior, and Immunity. 2025 Jan; 383-396. https://doi.org/10.1016/j.bbi.2024.09.030
Lisi I, Moro F, Mazzone E, Marklund N, Pischiutta F, Kobeissy F, Mao X, Corrigan F, Helmy A, Nasrallah F, Pietro VD, Ngwenya LB, Portela LV, Semple BD, Schneider ALC, Arrastia RD, Menon DK, Smith DH, Wellington C, Loane DJ, Wang KKW, Zanier ER. Exploiting blood-based biomarkers to align preclinical models with human traumatic brain injury. Brain. 2025 Apr 3;148(4):1062-1080. doi: 10.1093/brain/awae350. PMID: 39514789; PMCID: PMC11967814.
2024
Goubran M, Spaner C, Stukas S, Zoref-Lorenz A, Shojania K, Beckett M, Li A, Peterson E, Sekhon M, Grey R, Wellington C, Cheng CV, Biggs CM, Mattman A, Jordan MB, Chen LYC, Setiadi A. The role of C-reactive protein and ferritin in the diagnosis of HLH, adult-onset still’s disease, and COVID-19 cytokine storm. Sci Rep. 2024 Dec 28;14(1):31306. doi: 10.1038/s41598-024-82760-6. PMID: 39732949; PMCID: PMC11682105.
Chertkow H, Phillips N, Rockwood K, Anderson N, Andrew MK, Bartha R, Beaudoin C, Bélanger N, Bellec P, Belleville S, Bergman H, Best S, Bethell J, Bherer L, Black S, Borrie M, Camicioli R, Carrier J, Cashman N, Chan S, Crowshoe L, Cuello C, Cynader M, Dang-Vu T, Das S, Dixon RA, Ducharme S, Einstein G, Evans AC, Fahnestock M, Feldman H, Ferland G, Finger E, Fisk JD, Fogarty J, Fon E, Gan-Or Z, Gauthier S, Greenwood C, Henri-Bellemare C, Herrmann N, Hogan DB, Hsiung R, Itzhak I, Jacklin K, Lanctôt K, Lim A, MacKenzie I, Masellis M, Maxwell C, McAiney C, McGilton K, McLaurin J, Mihailidis A, Mohades Z, Montero-Odasso M, Morgan D, Naglie G, Nygaard H, O’Connell M, Petersen R, Pilon R, Rajah MN, Rapoport M, Roach P, Robillard JM, Rogaeva E, Rosa-Neto P, Rylett J, Sadavoy J, St George-Hyslop P, Seitz D, Smith E, Stefanovic B, Vedel I, Walker JD, Wellington C, Whitehead V, Wittich W. Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA). J Alzheimers Dis. 2024 Dec;102(3):535-561. doi: 10.1177/13872877241290990. Epub 2024 Dec 5. PMID: 39636028.
Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Paolo GD, Garretti F, Gate D, Golden LR, Heinecke JW, Herz J, Huang Y, Iadecola C, Johnson LA, Kanekiyo T, Karch CM, Khvorova A, Koppes-den Hertog SJ, Lamb BT, Lawler PE, Guen YL, Litvinchuk A, Liu CC, Mahinrad S, Marcora E, Marino C, Michaelson DM, Miller JJ, Morganti JM, Narayan PS, Naslavsky MS, Oosthoek M, Ramachandran KV, Ramakrishnan A, Raulin AC, Robert A, Saleh RNM, Sexton C, Shah N, Shue F, Sible IJ, Soranno A, Strickland MR, Tcw J, Thierry M, Tsai LH, Tuckey RA, Ulrich JD, van der Kant R, Wang N, Wellington CL, Weninger SC, Yassine HN, Zhao N, Bu G, Goate AM, Holtzman DM. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference. Alzheimers Dement. 2024 Sep;20(9):6590-6605. doi: 10.1002/alz.13877. Epub 2024 Jul 19. PMID: 39031528; PMCID: PMC11497726.
Esopenko C, Jain D, Adhikari SP, Dams-O’Connor K, Ellis M, Haag HL, Hovenden ES, Keleher F, Koerte IK, Lindsey HM, Marshall AD, Mason K, McNally JS, Menefee DS, Merkley TL, Read EN, Rojcyk P, Shultz SR, Sun M, Toccalino D, Valera EM, van Donkelaar P, Wellington C, Wilde EA. Intimate Partner Violence-Related Brain Injury: Unmasking and Addressing the Gaps. J Neurotrauma. 2024 Oct;41(19-20):2219-2237. doi: 10.1089/neu.2023.0543. Epub 2024 Apr 5. PMID: 38323539; PMCID: PMC11564844.
Thiara S, Stukas S, Hoiland R, Wellington C, Tymko M, Isac G, Finlayson G, Kanji H, Romano K, Hirsch-Reinshagen V, Sekhon M, Griesdale D. Characterizing the Relationship Between Arterial Carbon Dioxide Trajectory and Serial Brain Biomarkers with Central Nervous System Injury During Veno-Venous Extracorporeal Membrane Oxygenation: A Prospective Cohort Study. Neurocrit Care. 2024 Aug;41(1):20-28. doi: 10.1007/s12028-023-01923-x. Epub 2024 Feb 1. PMID: 38302643; PMCID: PMC11335840.
Sekhon MS, Stukas S, Hirsch-Reinshagen V, Thiara S, Schoenthal T, Tymko M, McNagny KM, Wellington C, Hoiland R. Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest. J Physiol. 2024 Nov;602(21):5731-5744. doi: 10.1113/JP284588. Epub 2023 Aug 28. PMID: 37639379.
Clarke ADA, Copas C, Hannon O, Padgett C, Knight JM, Falkenberg A, Varto H, Mason K, Wellington CL, van Donkelaar P, Marks J, Shultz SR, Symons GF. Detecting a hidden pandemic: The current state and future direction of screening and assessment tools for intimate partner violence-related brain injury. Neurosci Biobehav Rev. 2024 Oct 4;167:105912. doi: 10.1016/j.neubiorev.2024.105912. Epub ahead of print. PMID: 39368636.
Tabor JB, Penner LC, Galarneau JM, Josafatow N, Cooper J, Ghodsi M, Huang J, Fraser DD, Smirl J, Esser MJ, Yeates KO, Wellington CL, Debert CT, Emery CA. Plasma Biomarkers of Traumatic Brain Injury in Adolescents With Sport-Related Concussion. JAMA Netw Open. 2024 Sep 3;7(9):e2431959. doi: 10.1001/jamanetworkopen.2024.31959. PMID: 39235809; PMCID: PMC11378000.
Cooper JG, Ghodsi M, Stukas S, Leach S, Brooks-Wilson A, Wellington CL. APOE ε4 carrier status modifies plasma p-tau181 concentrations in cognitively healthy super-seniors. Alzheimers Dement. 2024 Jun;20(6):4373-4380. doi: 10.1002/alz.13804. Epub 2024 May 16. PMID: 38752508; PMCID: PMC11180846.
2023
Poliakova T, Wellington CL. Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia. Mol Neurodegener. 2023 Nov 16;18(1):86. doi: 10.1186/s13024-023-00671-y. PMID: 37974180; PMCID: PMC10652636.
Cooper JG, Stukas S, Ghodsi M, Ahmed N, Diaz-Arrastia R, Holmes DT, Wellington CL. Age specific reference intervals for plasma biomarkers of neurodegeneration and neurotrauma in a Canadian population. Clin Biochem. 2023 Nov;121-122:110680. doi: 10.1016/j.clinbiochem.2023.110680. Epub 2023 Oct 24. PMID: 37884086.
Stukas S, Cooper J, Higgins V, Holmes D, Adeli K, Wellington CL. Pediatric reference intervals for serum neurofilament light and glial fibrillary acidic protein using the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) cohort. Clin Chem Lab Med. 2023 Oct 27;62(4):698-705. doi: 10.1515/cclm-2023-0660. PMID: 37882772; PMCID: PMC10895925.
Tabor JB, Galarneau JM, Penner LC, Cooper J, Ghodsi M, Fraser DD, Wellington CL, Debert CT, Emery CA. Use of Biostatistical Models to Manage Replicate Error in Concussion Biomarker Research. JAMA Netw Open. 2023 Oct 2;6(10):e2339733. doi: 10.1001/jamanetworkopen.2023.39733. PMID: 37870831; PMCID: PMC10594140.
Cheng WH, Cheung H, Kang A, Fan J, Cooper J, Anwer M, Barron C, Wilkinson A, Hu G, Yue J, Cripton PA, Vocadlo DJ, Wellington CL. Altered Tau Kinase Activity in rTg4510 Mice after a Single Interfaced CHIMERA Traumatic Brain Injury. Int J Mol Sci. 2023 May 29;24(11):9439. doi: 10.3390/ijms24119439. PMID: 37298388; PMCID: PMC10253362.
Iadecola C, Smith EE, Anrather J, Gu C, Mishra A, Misra S, Perez-Pinzon MA, Shih AY, Sorond FA, van Veluw SJ, Wellington CL; American Heart Association Stroke Council Council on Arteriosclerosis Thrombosis and Vascular Biology Council on Cardiovascular Radiology and Intervention Council on Hypertension Council on Lifestyle and Cardiometabolic Health. The Neurovasculome: Key Roles in Brain Health and Cognitive Impairment: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke. 2023 Jun;54(6):e251-e271. doi: 10.1161/STR.0000000000000431. Epub 2023 Apr 3. PMID: 37009740; PMCID: PMC10228567.
Tabor JB, Penner LC, Cooper JG, Ghodsi M, Galarneau JM, Fraser DD, Emery CA, Wellington CL, Debert CT. Characterizing Factors Influencing Baseline Plasma Biomarkers for Sport-Related Concussion in Adolescents. J Neurotrauma. 2023 Aug;40(15-16):1638-1650. doi: 10.1089/neu.2022.0501. Epub 2023 Apr 6. PMID: 36852497.
Stukas S, Cooper J, Gill J, Fallah N, Skinnider MA, Belanger L, Ritchie L, Tsang A, Dong K, Streijger F, Street J, Paquette S, Ailon T, Dea N, Charest-Morin R, Fisher CG, Bailey CS, Dhall S, Mac-Thiong JM, Wilson JR, Christie S, Dvorak MF, Wellington CL, Kwon BK. Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury. Neurology. 2023 Mar 21;100(12):e1221-e1233. doi: 10.1212/WNL.0000000000206744. Epub 2023 Jan 4. PMID: 36599698; PMCID: PMC10033160.
2022
Messing M, Sekhon MS, Hughes MR, Stukas S, Hoiland RL, Cooper J, Ahmed N, Hamer MS, Li Y, Shin SB, Tung LW, Wellington CL, Sin DD, Leslie KB, McNagny KM. Prognostic peripheral blood biomarkers at ICU admission predict COVID-19 clinical outcomes. Front Immunol. 2022 Nov 14;13:1010216. doi: 10.3389/fimmu.2022.1010216. PMID: 36451808; PMCID: PMC9703061.
Cameron TC, Randhawa A, Grist SM, Bennet T, Hua J, Alde LG, Caffrey TM, Wellington CL, Cheung KC. PDMS Organ-On-Chip Design and Fabrication: Strategies for Improving Fluidic Integration and Chip Robustness of Rapidly Prototyped Microfluidic In Vitro Models. Micromachines (Basel). 2022 Sep 22;13(10):1573. doi: 10.3390/mi13101573. PMID: 36295926; PMCID: PMC9609846.
Stukas S, Goshua G, Kinkade A, Grey R, Mah G, Biggs CM, Jamal S, Thiara S, Lau TTY, Piszczek J, Partovi N, Sweet DD, Lee AYY, Wellington CL, Sekhon MS, Chen LYC. Reduced fixed dose tocilizumab 400 mg IV compared to weight-based dosing in critically ill patients with COVID-19: A before-after cohort study. Lancet Reg Health Am. 2022 Jul;11:100228. doi: 10.1016/j.lana.2022.100228. Epub 2022 Mar 23. PMID: 35345649; PMCID: PMC8941850.
Hoiland RL, Rikhraj KJK, Thiara S, Fordyce C, Kramer AH, Skrifvars MB, Wellington CL, Griesdale DE, Fergusson NA, Sekhon MS. Neurologic Prognostication After Cardiac Arrest Using Brain Biomarkers: A Systematic Review and Meta-analysis. JAMA Neurol. 2022 Apr 1;79(4):390-398. doi: 10.1001/jamaneurol.2021.5598. PMID: 35226054; PMCID: PMC8886448.
Leatherdale A, Stukas S, Lei V, West HE, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzdial ELG, Conway EM. Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality. Med Microbiol Immunol. 2022 Feb;211(1):37-48. doi: 10.1007/s00430-021-00725-2. Epub 2022 Jan 16. PMID: 35034207; PMCID: PMC8761108.
Vavasour IM, Becquart P, Gill J, Zhao G, Yik JT, Traboulsee A, Carruthers RL, Kolind SH, Schabas AJ, Sayao AL, Devonshire V, Tam R, Moore GRW, Stukas S, Wellington CL, Quandt JA, Li DKB, Laule C. Diffusely abnormal white matter in clinically isolated syndrome is associated with parenchymal loss and elevated neurofilament levels. Mult Scler Relat Disord. 2022 Jan;57:103422. doi: 10.1016/j.msard.2021.103422. Epub 2021 Nov 26. PMID: 34871858.
2021
Hoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson NA, Conway EM, Menon DK, Gooderham P, Hirsch-Reinshagen V, Griesdale DE, Sekhon MS. Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Circ Res. 2021 Aug 20;129(5):583-597. doi: 10.1161/CIRCRESAHA.121.319157. Epub 2021 Jul 21. PMID: 34287000; PMCID: PMC8376277.
Cameron T, Bennet T, Rowe EM, Anwer M, Wellington CL, Cheung KC. Review of Design Considerations for Brain-on-a-Chip Models. Micromachines (Basel). 2021 Apr 15;12(4):441. doi: 10.3390/mi12040441. PMID: 33921018; PMCID: PMC8071412.
Chen LYC, Biggs CM, Jamal S, Stukas S, Wellington CL, Sekhon MS. Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome. Cell Rep Med. 2021 May 18;2(5):100269. doi: 10.1016/j.xcrm.2021.100269. Epub 2021 Apr 19. PMID: 33899032; PMCID: PMC8055165.
Button EB, Cheng WH, Barron C, Cheung H, Bashir A, Cooper J, Gill J, Stukas S, Baron DC, Robert J, Rowe EM, Cripton PA, Wellington CL. Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury. Alzheimers Res Ther. 2021 Mar 7;13(1):58. doi: 10.1186/s13195-021-00793-9. PMID: 33678186; PMCID: PMC7938597.
Chen LYC, Hoiland RL, Stukas S, Wellington CL, Sekhon MS. Assessing the importance of interleukin-6 in COVID-19. Lancet Respir Med. 2021 Feb;9(2):e13. doi: 10.1016/S2213-2600(20)30600-7. Epub 2021 Jan 15. PMID: 33460569; PMCID: PMC7836242.
Wang KK, Munoz Pareja JC, Mondello S, Diaz-Arrastia R, Wellington C, Kenney K, Puccio AM, Hutchison J, McKinnon N, Okonkwo DO, Yang Z, Kobeissy F, Tyndall JA, Büki A, Czeiter E, Pareja Zabala MC, Gandham N, Berman R. Blood-based traumatic brain injury biomarkers – Clinical utilities and regulatory pathways in the United States, Europe and Canada. Expert Rev Mol Diagn 2021 Dec;21(12):1303-1321. doi: 10.1080/14737159.2021.2005583
England JT, Abdulla A, Biggs CM, Lee AYY, Hay KA, Hoiland RL, Wellington CL, Sekhon M, Jamal S, Shojania K, Chen LYC. Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes. Blood Rev. 2021 Jan;45:100707. doi: 10.1016/j.blre.2020.100707. Epub 2020 May 15. PMID: 32425294; PMCID: PMC7227559.
2020
Stukas S, Hoiland RL, Cooper J, Thiara S, Griesdale DE, Thomas AD, Orde MM, English JC, Chen LYC, Foster D, Mitra AR, Romano K, Sweet DD, Ronco JJ, Kanji HD, Chen YR, Wong SL, Wellington CL, Sekhon MS. The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Critically Ill Patients With Coronavirus Disease 2019. Crit Care Explor. 2020 Sep 17;2(9):e0203. doi: 10.1097/CCE.0000000000000203. PMID: 33063041; PMCID: PMC7515615.
Cooper J, Stukas S, Hoiland RL, Fergusson NA, Thiara S, Foster D, Mitra A, Stoessl JA, Panenka WJ, Sekhon MS, Wellington CL. Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019. Crit Care Explor. 2020 Oct 2;2(10):e0238. doi: 10.1097/CCE.0000000000000238. PMID: 33063038; PMCID: PMC7535554.
Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, Cooper J, Thiara S, Foster D, Chen LYC, Lee AYY, Conway EM, Wellington CL, Sekhon MS. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19. Blood Adv. 2020 Oct 27;4(20):4981-4989. doi: 10.1182/bloodadvances.2020002623. PMID: 33057633; PMCID: PMC7594392.
Chen LYC, Hoiland RL, Stukas S, Wellington CL, Sekhon MS. Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome. Eur Respir J. 2020 Oct 1;56(4):2003006. doi: 10.1183/13993003.03006-2020. PMID: 32883678; PMCID: PMC7474149.
Hoiland RL, Stukas S, Cooper J, Thiara S, Chen LYC, Biggs CM, Hay K, Lee AYY, Shojania K, Abdulla A, Wellington CL, Sekhon MS. Amelioration of COVID-19-related cytokine storm syndrome: parallels to chimeric antigen receptor-T cell cytokine release syndrome. Br J Haematol. 2020 Aug;190(3):e150-e154. doi: 10.1111/bjh.16961. Epub 2020 Jul 16. PMID: 32584416; PMCID: PMC7361645.
Cable J, Holtzman DM, Hyman BT, Tansey MG, Colonna M, Kellis M, Brinton RD, Albert M, Wellington CL, Sisodia SS, Tanzi RE. Alternatives to amyloid for Alzheimer’s disease therapies-a symposium report. Ann N Y Acad Sci. 2020 Sep;1475(1):3-14. doi: 10.1111/nyas.14371. Epub 2020 May 29. PMID: 32472577; PMCID: PMC9621603.
2019
Gibbs E, Silverman JM, Zhao B, Peng X, Wang J, Wellington CL, Mackenzie IR, Plotkin SS, Kaplan JM, Cashman NR. A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease. Sci Rep. 2019 Jul 8;9(1):9870. doi: 10.1038/s41598-019-46306-5. PMID: 31285517; PMCID: PMC6614461.
Stukas S, Higgins V, Frndova H, Gill J, Hubara E, Guerguerian A-M, Boutis K, Beauchamp M, Farrell C, Babl FE, Delzoppo C, Greenham M, Wilkinson AA, Crichton A, Anderson V, Adeli K, Hutchison J, Wellington C. Characterisation of serum total tau following paediatric traumatic brain injury: a case-control study. Lancet Child Adolesc Health 2019 Aug;3(8):558-567. doi: 10.1016/S2352-4642(19)30194-4.
2018
Cheng WH, Stukas S, Martens KM, Namjoshi DR, Button EB, Wilkinson A, Bashir A, Robert J, Cripton PA, Wellington CL. Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice. Exp Neurol. 2018 Mar;301(Pt A):26-38. doi: 10.1016/j.expneurol.2017.12.007. Epub 2017 Dec 18. PMID: 29269117
2017
Vonder Haar C, Martens KM, Riparip LK, Rosi S, Wellington CL, Winstanley CA. Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12. J Neurotrauma. 2017 Oct 1;34(19):2790-2800. doi: 10.1089/neu.2016.4813. Epub 2017 May 24. PMID: 28376700; PMCID: PMC5647497
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